Stand Up Therapeutics

Publications and patents


- 10-2021-0190556 운동성 신경세포 직접교차 분화용 인자
- 10-2023-0083845 척수 손상 질환을 치료하기 위한 조성물 및 이의 이용
- 10-2023-0106523 신경계질환을 치료하기 위한 조성물 및 이를 이용하는 신경계질환을 치료하는 방법
- 10-2023-0127277 신규한 파킨슨병 치료제


- 제 10-2594254 호 운동성 신경세포 직접교차 분화용 인자


- PCT/KR2022/021615 운동성 신경세포 직접교차 분화용 인자
- PCT/KR2023/009608 척수 손상 질환을 치료하기 위한 조성물 및 이의 이용



First author

Corresponding author

- Chang Y, Lee SW, Kim J, Kim CG, Shim HS, Lee SE, Park HJ, Kim JW, Lee SH, Lee YK, Park SH, Yoo J** Gene Therapy Using Efficient Direct Lineage Reprogramming Technology for Neurological Diseases. Nanomaterials. 2023. May. (IF: 5.719)
- Kim CG, Shim HS, Chang Y, Lim HJ, Yoo J** Novel Gene Therapies Technology for Spinal Cord Injury(SCI) Therapy : Efficient Direct Lineage Reprogramming. Journal of Clinical Pharmacology and Therapeutics. 2022. Oct.
- Lee S, Park J, Han YE, Oh S, Lee W, Im H, Seol Y, Park S, Yoo J** Elongated nanoporous Au networks mediate somatic cell direct conversion into induced dopaminergic neurons for Parkinson’s disease therapy. Acta Biomaterialia. 2022 Aug. (IF:10.6)
- Yoo J*, Kim J, Lee JH, Kim H, Jang SJ, Seo HH, Oh ST, Hyeon SJ, Ryu H, Kim J, Moh SH. Acceleration of somatic cell reprogramming into the induced pluripotent stem cell using a mycosporine-like amino acid, Porphyra 334. Nature Scientific Reports. 2020 Feb 28;10(1):3684. (IF:4.122)
- Yoo J*, Lee E, Kim HY, Youn DH, Jung J, Kim H, Chang Y, Lee W, Shin J, Baek S, Jang W, Jun W, Kim S, Hong J, Park HJ, Lengner CJ, Moh SH, Kwon Y, Kim J. Electromagnetized gold nanoparticles mediate direct lineage reprogramming into induced dopamine neurons in vivo for Parkinson's disease therapy. Nature Nanotechnology. 2017 Oct;12(10):1006-1014. (IF:43.341)
- Yoo J*, Chang Y, Kim H, Baek S, Choi H, Jeong GJ, Shin J, Kim H, Kim BS, Kim J. Efficient Direct Lineage Reprogramming of Fibroblasts into Induced Cardiomyocytes Using Nanotopographical Cues. Journal of Biomedical Nanotechnology. 2017 Mar;13(3):269-79. (IF:5.068)
- Park JY*, Kim SN*, Yoo J*, Jang J, Lee A, Oh JY, Kim H, Oh ST, Park SU, Kim J, Park HJ, Jeon S. Novel Neuroprotective Effects of Melanin-Concentrating Hormone in Parkinson's Disease. Molecular Neurobiology. 2017 Dec;54(10):7706-7721. (IF:4.586)
- Yoo J*, Kim J, Baek S, Park Y, Im H, Kim J. Cell reprogramming into the pluripotent state using graphene based substrates. Biomaterials. 2014 Sep;35(29):8321-9. (IF:10.273)
- Park H, Oh J, Shim G, Cho B, Chang Y, Kim S, Baek S, Kim H, Shin J, Choi H, Yoo J, Kim J, Jun W, Lee M, Lengner CJ, Oh YK, Kim J. In vivo neuronal gene editing via CRISPR-Cas9 amphiphilic nanocomplexes alleviates deficits in mouse models of Alzheimer's disease. Nature Neuroscience. 2019 Apr;22(4):524-528. (IF:21.126)
- Kim YK, Lee AR, Park H, Yoo J, Ahn S, Jeon SH, Kim J, Park HJ. Acupuncture Alleviates LevodopaInduced Dyskinesia via Melanin-Concentrating Hormone in Pitx3-Deficient aphakia and 6- Hydroxydopamine-Lesioned Mice. Molecular Neurobiology. 2019 Apr;56(4):2408-2423. (IF:4.586)
- Chang Y, Yoo J, Kim H, Park HJ, Jeon S, Kim J. Salusin-β mediate neuroprotective effects for Parkinson's disease. Biochemical and Biophysical Research Communications. 2018 Sep 10;503(3):1428-1433. (IF:2.559)
- Kim H, Yoo J, Shin J, Chang Y, Jung J, Jo DG, Kim J, Jang W, Lengner CJ, Kim BS, Kim J. Modelling APOE ɛ3/4 allele-associated sporadic Alzheimer's disease in an induced neuron. Brain. 2017 Aug 1;140(8):2193-2209. doi: 10.1093/brain/awx144. (IF:11.814)
- Baek S, Oh J, Song J, Choi H, Yoo J, Park GY, Han J, Chang Y, Park H, Kim H, Cho SG, Kim BS, Kim J. Generation of Integration-Free Induced Neurons Using Graphene Oxide-Polyethylenimine. Small. 2017 Feb;13(5). (IF:10.856)